MT2 (Melanotan II) is a synthetic cyclic heptapeptide supplied by Echo Peptides strictly for laboratory and in-vitro research. Structurally an analog of alpha-melanocyte-stimulating hormone (alpha-MSH), it incorporates a lactam bridge that constrains the peptide backbone, a modification researchers associate with increased conformational stability and receptor affinity relative to the native ligand.

As a reference compound in melanocortin pharmacology, MT2 is used in cell-culture and preclinical model systems to probe the melanocortin receptor family (MC1R through MC5R). Its non-selective agonist profile makes it a common tool for investigators mapping receptor-mediated signaling and comparing responses across melanocortin subtypes in vitro.

Key research areas

  • Melanocortin receptor (MC1R–MC5R) signaling and agonist profiling in cell-culture models
  • Pigmentation and melanin-synthesis pathways in melanocyte-based in-vitro systems
  • Appetite regulation and energy-balance mechanisms in preclinical research models
  • Neuroendocrine signaling studies involving melanocortin pathways
  • Structure–activity comparisons between cyclic analogs and native alpha-MSH

Specifications

  • Amount: 10mg per vial
  • Form: Lyophilized white powder
  • Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
  • Molecular weight: 1024.2 Da
  • Solubility: Soluble in bacteriostatic water and common research buffers
  • Storage: Refrigerate at 2–8°C; long-term stability when lyophilized
  • Quality: Third-party tested for identity and purity; a Certificate of Analysis is available on request

This product is intended for laboratory and in-vitro research use only and is not for human or veterinary use.